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Bispecific chimeric antigen receptors targeting the CD4 binding site and high-mannose Glycans of gp120 optimized for anti–human immunodeficiency virus potency and breadth with minimal immunogenicity

Minimal ImmunogenicityHuman RetrovirusImmunodeficienciesGlycobiologyImmunologyCd4 Binding SiteAntiviral ResponseImmunotherapeuticsCd4 T Cell ResponsesHivImmunotherapyMedicineViral ImmunityHigh-mannose GlycansBiomolecular EngineeringGlycosylation