Concepedia

Correlation of interleukin-33 with Th cytokines and clinical severity of dry eye disease

Guoping Luo, Yan Ping Xin, Dajun Qin, A. Yan, Zhiyan Zhou, Zhaoxia Liu

Indian Journal of Ophthalmology · 2017 · 23 citations · 24 references

DOIFull text

Open access

Abstract

Elevated tear levels of IL-33 were associated with the Th2 cytokines and disease severity of DE. Therefore, IL-33 may have important roles in the immunopathogenesis of the DE.

References

24

IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines

Jochen Schmitz, Alexander M. Owyang, Elizabeth R. Oldham et al. · Immunity · 2005 · 3.6K citations · Full text

, , +7

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

Daniel R. Neill, See Heng Wong, Agustin Bellosi et al. · Nature · 2010 · 2K citations · Full text

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Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

Kazuyo Moro, Taketo Yamada, M. Tanabe et al. · Nature · 2009 · 1.9K citations

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Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes.

Michael A. Lemp · PubMed · 1995 · 1.7K citations

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IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells

Molly D. Smithgall, Michael R. Comeau, Bo Ruem Yoon et al. · International Immunology · 2008 · 602 citations · Full text

, , +20