Safety Profile and Efficacy of Ivabradine in Heart Failure Due to Chagas Heart Disease: A <i>Post Hoc</i> Analysis of the SHIFT Trial

Abstract

ChD HF is an advanced form of HF with poor prognosis. Ivabradine was effective in reducing HR in these patients and improving functional class. Although our results are based on a very limited sample and should be interpreted with caution, they suggest that ivabradine may have a favourable benefit-risk profile in ChD HF patients.