Concepedia

A high 18F-FDOPA uptake is associated with a slow growth rate in diffuse Grade II–III gliomas

Sibel Isal, Guillaume Gauchotte, Fabien Rech, Marie Blonski, Sophie Planel, Mohammad B. Chawki, Gilles Karcher, Pierre‐Yves Marie, Luc Taillandier, Antoine Verger

British Journal of Radiology · 2017 · 20 citations · 10 references

DOIFull text

Open access

Abstract

This pilot study shows that in diffuse Grade II-III gliomas, a high <sup>18</sup>F-FDOPA uptake would be predictive of low tumour growth, with a different prognostic significance than IDH mutation. Advances in knowledge: <sup>18</sup>F-FDOPA PET in a single session imaging could have prognostic value in initial diagnosis of diffuse Grade II-III gliomas.

References

10

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

Zachary J. Reitman, Genglin Jin, Edward D. Karoly et al. · Proceedings of the National Academy of Sciences · 2011 · 448 citations

Velocity of tumor spontaneous expansion predicts long-term outcomes for diffuse low-grade gliomas

Johan Pallud, Marie Blonski, Emmanuel Mandonnet et al. · Neuro-Oncology · 2013 · 169 citations · Full text

IDH mutation status impact on in vivo hypoxia biomarkers expression: new insights from a clinical, nuclear imaging and immunohistochemical study in 33 glioma patients

Philippe Métellus, Carole Colin, David Taïeb et al. · Journal of Neuro-Oncology · 2011 · 67 citations

, , +13

IDH mutation is paradoxically associated with higher 18F-FDOPA PET uptake in diffuse grade II and grade III gliomas

Antoine Verger, P. Métellus, Quentin Sala et al. · European Journal of Nuclear Medicine and Molecular Imaging · 2017 · 66 citations · Full text

, , +14

Oligodendroglial component complicates the prediction of tumour grading with metabolic imaging

Osamu Manabe, Naoya Hattori, Shigeru Yamaguchi et al. · European Journal of Nuclear Medicine and Molecular Imaging · 2015 · 54 citations

, , +11