Journal of the National Comprehensive Cancer Network · 2017 · 215 citations · 33 references
Life SciencesGeneticsOncologyCancer GeneticsMedical GeneticsRisk AssessmentColorectal CancerGenetic Risk AssessmentGenetic Risk FactorsGermline Cancer PredispositionHereditary Cancer SyndromesHereditary Gastrointestinal Cancer SyndromesColorectal Cancer PredispositionFamilial Cancer RiskFamilial Colorectal CancerHereditary Colorectal Cancer SyndromesHereditary Nonpolyposis Colorectal CancerInherited Cancer RiskMultigene Panel TestingMultigene Panels
The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the management of patients with high-risk syndromes associated with an increased risk of colorectal cancer (CRC). The NCCN Panel for Genetic/Familial High-Risk Assessment: Colorectal meets at least annually to assess comments from reviewers within their institutions, examine relevant data, and reevaluate and update their recommendations. These NCCN Guidelines Insights focus on genes newly associated with CRC risk on multigene panels, the associated evidence, and currently recommended management strategies.
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Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk
Douglas F. Easton, Paul D.P. Pharoah, Antonis C. Antoniou et al. · New England Journal of Medicine · 2015 · 937 citations · Full text
Life Sciences, Genetics, Oncology +17
Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC
Steven J. Laken, Gloria M. Petersen, Stephen B. Gruber et al. · Nature Genetics · 1997 · 689 citations