Concepedia

Soluble Epoxide Hydrolase Plays a Vital Role in Angiotensin II-Induced Lung Injury in Mice

Wei Tao, Pingsong Li, Gang Xú, Yi Luo, Yusheng Shu, Yong-Zhong Tao, Liuqing Yang

Shock · 2017 · 22 citations · 28 references

DOI

Abstract

Angiotensin II-induced lung injury was improved in sEH gene deleted mice. The angiotensin II-triggered pulmonary inflammation is mediated, at least in part, through the sEH.

References

28

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Ards Definition Task Force · JAMA · 2012 · 8.7K citations

Tissue Destruction by Neutrophils

New England Journal of Medicine · 1989 · 3.6K citations

, , +19

Soluble epoxide hydrolase is a therapeutic target for acute inflammation

Kara Schmelzer, Lukáš Kubala, John W. Newman et al. · Proceedings of the National Academy of Sciences · 2005 · 439 citations · Full text

Soluble Epoxide Hydrolase Inhibition Lowers Arterial Blood Pressure in Angiotensin II Hypertension

John D. Imig, Xueying Zhao, Jorge H. Capdevila et al. · Hypertension · 2002 · 397 citations · Full text

, , +16

Targeted Disruption of Soluble Epoxide Hydrolase Reveals a Role in Blood Pressure Regulation

Christopher J. Sinal, Masaaki Miyata, Masahiro Tohkin et al. · Journal of Biological Chemistry · 2000 · 340 citations · Full text