Concepedia

PGAM5 regulates PINK1/Parkin-mediated mitophagy via DRP1 in CCCP-induced mitochondrial dysfunction

Yun Sun Park, Su Eun Choi, Hyun Chul Koh

Toxicology Letters · 2017 · 184 citations · 34 references

DOI

Concepts

References

34

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Derek P. Narendra, Atsushi Tanaka, Der‐Fen Suen et al. · The Journal of Cell Biology · 2008 · 4K citations · Full text

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Gilad Twig, Álvaro A. Elorza, Anthony Molina et al. · The EMBO Journal · 2008 · 3.1K citations · Full text

, , +12

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra, Seok Min Jin, Atsushi Tanaka et al. · PLoS Biology · 2010 · 2.9K citations · Full text

, , +17

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

Noriyuki Matsuda, Shigeto Sato, Kahori Shiba et al. · The Journal of Cell Biology · 2010 · 1.9K citations · Full text

, , +17

The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis

Stephan Frank, Brigitte Gaume, Elke S. Bergmann‐Leitner et al. · Developmental Cell · 2001 · 1.7K citations · Full text

, , +13