Concepedia

Publication | Open Access

DNAzyme based visual detection of DNA methylation

DOIFull Paper Access

17

Citations

14

References

2017

Year

Mei Li, Lei Zhang, Gangyi Chen, Jing Zhou, Yi Yuan, Jiawei Zou, Mingming Yuan, Rong Chen, Feng Du, Xin Cui,
Chemical Communications

Abstract

A novel colorimetric method which utilizes DNAzyme as a signal reporter was developed for DNA methylation detection. As low as 1/10<sup>6</sup> of methylated DNA could be successfully detected from unmethylated DNA. The discrimination ability is at least two orders of magnitude better than that of the methylation specific PCR.

References

YearCitations

Page 1