Usefulness of the Martin Method for Estimation of Low-Density Lipoprotein Cholesterol in Coronary Atherosclerosis

Abstract

The Martin method to estimate LDL-C using the strata-specific TG:VLDL ratio showed a 2-fold better concordance with LDL-C measured with a direct homogeneous assay in coronary atherosclerosis compared to the Friedewald equation when the TG level was ≥200 mg/dL. This finding suggests that MLDL could be a better alternative for estimating LDL-C compared to FLDL when the TG level is ≥200 mg/dL in coronary atherosclerosis.