Growth of Microorganisms in Parenteral Nutritional Fluids

Abstract

A number of parenteral fluids were assessed as substrates for bacterial and yeast growth. No microorganism underwent significant growth in any solution during the first 24 hours of incubation at room temperature with the exception of Candida albicans, which proliferated in a casein hydrolysate TPN solution. A crystalline amino acid TPN solution is a poor growth medium for microorganisms as compared to the casein hydrolysate solution. Suggestions are made relative to the preparation and proper use of TPN solutions in adult and pediatric hyperalimentation.