Nature Protocols · 2017 · 121 citations · 40 references
PharmacyCell BiologyMolecular BiologyAntibody EngineeringCellular ImmunologyMonoclonal AntibodiesAntibody CharacterizationAntibody Expression SystemsAntibody FunctionAntibody-antigen RecognitionHybridoma TechnologyRecombinant AntibodiesAntibodiesHuman Antibody-producing ModelsTransfection In Mammalian CellsTransient ExpressionTransient Expression SystemsTransient Expression VectorsTransient Gene Expression
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Continuous cultures of fused cells secreting antibody of predefined specificity
Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations
Pharmacy, Cell Biology, Immunology +11
Raise standards for preclinical cancer research
C. Glenn Begley, Lee M. Ellis · Nature · 2012 · 2.9K citations · Full text
Medicine, Cancer Biology, Oncology +12
Reshaping human antibodies for therapy
Lutz Riechmann, Herman Waldmann, Greg Winter · Nature · 1988 · 1.6K citations
Replacing the complementarity-determining regions in a human antibody with those from a mouse
Peter Jones, Paul H. Dear, Jefferson Foote et al. · Nature · 1986 · 1.4K citations
Making antibody fragments using phage display libraries
Tim Clackson, Hennie R. Hoogenboom, Andrew D. Griffiths et al. · Nature · 1991 · 1.2K citations