Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells

Abstract

Allogeneic hematopoietic stem cell transplantation (allo-SCT) is an effective treatment for hematologic malignancies. The most frequent cause of post-transplant mortality is disease relapse, the majority of the cases present recurrence of original disease from outgrowth of residual cells having