Evaluation of short exposure times of antimicrobial wound solutions against microbial biofilms: from in vitro to in vivo

Abstract

Short durations of exposure to topical antimicrobial wound solutions commonly utilized by clinicians are ineffective against microbial biofilms, particularly when used in vivo. Wound solutions should not be used as a sole therapy and clinicians should consider multifaceted strategies that include sharp debridement as the gold standard.