A Randomized Controlled Trial of Low-Dose Tranexamic Acid versus Placebo to Reduce Red Blood Cell Transfusion During Complex Multilevel Spine Fusion Surgery

Intraoperative Transfusion of 1 U to 2 U Packed Red Blood Cells Is Associated with Increased 30-Day Mortality, Surgical-Site Infection, Pneumonia, and Sepsis in General Surgery Patients

Andrew C. Bernard, Daniel L. Davenport, Phillip Chang et al. · Journal of the American College of Surgeons · 2009 · 487 citations

Medicine, Perioperative Medicine, Surgery +17

High-Dose Tranexamic Acid Is Associated with Nonischemic Clinical Seizures in Cardiac Surgical Patients

John M. Murkin, Florian Falter, Jeff Granton et al. · Anesthesia & Analgesia · 2010 · 378 citations

Medicine, Perioperative Medicine, Surgery +12

Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients

Andrew Retter, Duncan Wyncoll, Rupert M. Pearse et al. · British Journal of Haematology · 2012 · 257 citations · Full text

Medicine, Hematology, Hemostasis +16

Efficacy and Safety of Prophylactic Large Dose of Tranexamic Acid in Spine Surgery

Sherif Elwatidy, Zain Jamjoom, Essam A. Elgamal et al. · Spine · 2008 · 215 citations

Medicine, Neurosurgery, Surgery +17

Tranexamic Acid Reduces Perioperative Blood Loss in Adult Patients Having Spinal Fusion Surgery

Jean Wong, Hossam El Beheiry, Y. Raja Rampersaud et al. · Anesthesia & Analgesia · 2008 · 211 citations

Medicine, Perioperative Medicine, Surgery +17