Meibomian Glands and Ocular Surface Changes After Closure of Meibomian Gland Orifices in Rabbits

Abstract

Meibomian gland orifice closure reduced corneal wetting property and induced meibomian gland duct dilation accompanied by shrinkage of secretory acini. Meibography could not detect early changes in the meibomian gland after closure of the orifice. Therefore, when the orifice is obstructed, more active treatments are needed before structural changes occur.