Silver-catalyzed synthesis of pyrrolopiperazine fused with oxazine/imidazole <i>via</i> a domino approach: evaluation of anti-cancer activity

Abstract

Ag-Catalyzed synthesis of pyrrolopiperazine fused with oxazine/imidazole by the reaction of δ-alkynyl aldehydes and nucleophilic amines was performed. Several of these compounds were found to exhibit anti-cancer activity against cancer cell lines.