Indian Journal of Nephrology · 2017 · 62 citations · 33 references
MedicineEndocrinologyNephrologyDiabetologyRenal PathologyRenal PathophysiologyDiabetes MellitusDiabetic Kidney DiseaseDiabetic NephropathyRenal DiseaseRenal Function TestsRenal ImpairmentCreatinine-based BiomarkersGlomerular Filtration Rate MeasurementNeutrophil Gelatinase-associated LipocalinPrognostic IndicesSerum BiomarkersSerum Creatinine AssessmentSerum SamplingTubular Injury Assessment
< 0.05). Tubular injury may precede glomerular injury in diabetic individuals, and NGAL can be used as a biomarker to diagnose DN even earlier to incipient nephropathy. Both sNGAL and uNGAL can predict albuminuria and be used as a noninvasive tool for diagnosis, staging, and progression of DN.
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Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
Trude Helen Flo, Kelly D. Smith, Shintaro Sato et al. · Nature · 2004 · 1.9K citations