Concepedia

Publication | Open Access

A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma

DOIFull Paper Access

33

Citations

38

References

2017

Year

Dan R. Laks, Juan A. Osés-Prieto, Alvaro G. Alvarado, Jonathan Nakashima, Shreya Chand, Daniel Azzam, Ankur A. Gholkar, Jantzen Sperry, Kirsten Ludwig, Michael Condro,
Neuro-Oncology

Abstract

These data portray a compensatory molecular signaling network that imparts resistance to chronic mTOR inhibition in primary, human GBM cell cultures and points toward new therapeutic strategies.

References

YearCitations

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