Israel Journal of Chemistry · 2017 · 31 citations · 78 references
NanomedicineMedicinal ChemistryPhotochemistryPolymer-drug ConjugatePhotodynamic TherapyMedicineTherapeutic NanomaterialsPhototoxicityMolecular ContainersDrug Delivery SystemsCancer TreatmentPhotosensitizersPharmacologyRadiation OncologyBiophysicsDrug DiscoveryHealth Sciences
Abstract Cucurbit[ n ]urils (CB[ n ]s) have emerged as potential candidates for drug delivery in several areas due to their strong binding interactions and low toxicity. More recently, their benefits for a type of cancer treatment termed Photodynamic Therapy (PDT) have been recognized. The outcomes of this therapy rely on better drug delivery strategies and improving overall photoactivity of the drugs, which is where CB[ n ]s could have a strong impact. The effects of these molecular containers on photoactivity are discussed and new interesting work is highlighted.
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