Accumulation of Antigen‐Driven Lymphoproliferations in Complement Receptor 2/<scp>CD</scp>21^−/low B Cells From Patients With Sjögren's Syndrome

Abstract

Clonal lymphoproliferations in patients with SS preferentially accumulate in the autoreactive CD21^-/low B cell compartment often expanded in these subjects, and recognition of self antigens may drive the clonal B cell expansion while further refining BCR self-reactivity.