Publication | Open Access

Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors

Medicinal ChemistryAldehyde DehydrogenaseBiochemistryNatural SciencesIndane AnaloguesRational Drug DesignMolecular BiologyConformational StudyChemical BiologyStructure-function Enzyme KineticsDrug DiscoveryStructure-activity-relationship Study