Concepedia

Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma

Keisuke Kataoka, Masako Iwanaga, Jun‐ichirou Yasunaga, Yasunobu Nagata, Akira Kitanaka, Takuro Kameda, Makoto Yoshimitsu, Yuichi Shiraishi, Aiko Sato‐Otsubo, Masashi Sanada,

Blood · 2017 · 158 citations · 29 references

DOIFull text

Open access

Concepts

Abstract

amplifications are a strong genetic predictor in both aggressive and indolent ATL. ATL subtypes are further classified into molecularly distinct subsets with different prognosis. Genetic profiling might contribute to improved prognostication and management of ATL patients.

References

29

Genomic Classification and Prognosis in Acute Myeloid Leukemia

Elli Papaemmanuil, Moritz Gerstung, Lars Bullinger et al. · New England Journal of Medicine · 2016 · 4.4K citations · Full text

, , +14

Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray

Christine P. Hans · Blood · 2003 · 4.3K citations · Full text

, , +16

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

Craig H. Mermel, Steven E. Schumacher, Barbara Hill et al. · Genome biology · 2011 · 3.9K citations · Full text

, , +15

PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma

Stephen M. Ansell, Alexander M. Lesokhin, Ivan Borrello et al. · New England Journal of Medicine · 2014 · 3.5K citations · Full text

, , +17

Clinical Effect of Point Mutations in Myelodysplastic Syndromes

Rafael Bejar, Kristen E. Stevenson, Omar Abdel‐Wahab et al. · New England Journal of Medicine · 2011 · 1.6K citations

, , +17