Concepedia

Achieving efficient photodynamic therapy under both normoxia and hypoxia using cyclometalated Ru(<scp>ii</scp>) photosensitizer through type I photochemical process

Zhuang Lv, Huanjie Wei, Qing Li, Xianlong Su, Shujuan Liu, Kenneth Yin Zhang, Wen Lv, Qiang Zhao, Xianghong Li, Wei Huang

Chemical Science · 2017 · 263 citations · 43 references

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Concepts

Abstract

A type I Ru(<sc>ii</sc>) photosensitizer retained an excellent PDT effect under hypoxia through the formation of highly-oxidative hydroxyl radicals under light irradiation.

References

43

Highly Phosphorescent Bis-Cyclometalated Iridium Complexes:  Synthesis, Photophysical Characterization, and Use in Organic Light Emitting Diodes

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Mechanisms in photodynamic therapy: part one—photosensitizers, photochemistry and cellular localization

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Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix.

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Mechanism of Photogenerated Reactive Oxygen Species and Correlation with the Antibacterial Properties of Engineered Metal-Oxide Nanoparticles

Yang Li, Wen Zhang, Junfeng Niu et al. · ACS Nano · 2012 · 1.6K citations

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A graphene quantum dot photodynamic therapy agent with high singlet oxygen generation

Jiechao Ge, Minhuan Lan, Bingjiang Zhou et al. · Nature Communications · 2014 · 1.4K citations · Full text

, , +17