Pilot Study Measuring the Novel Satiety Hormone, Pro‐Uroguanylin, in Adolescents With and Without Obesity

Abstract

In adolescents with and without obesity, we can measure circulating pro-uroguanylin levels. In female adolescents without obesity, levels are particularly higher. Pro-uroguanylin secretion patterns differ from other circulating gastrointestinal peptides. In female adolescents with obesity, inflammation correlates with decreased pro-uroguanylin levels.