OneFlorida Clinical Research Consortium: Linking a Clinical and Translational Science Institute With a Community-Based Distributive Medical Education Model

TLDR

Developing a national pragmatic clinical trial infrastructure is central to understanding the effectiveness of interventions applied under usual conditions and where people receive health care. The consortium was created to support pragmatic clinical trials and provide mentored research experiences for medical and graduate students in real‑world practice settings. The OneFlorida Clinical Research Consortium comprises four programs—Clinical Research, Citizen Scientist, Data Trust, and Minority Education—providing research support, community clinician engagement, large‑scale EHR and claims data, and minority faculty mentoring across Florida’s community practice settings. To date, OneFlorida has implemented 27 studies with diverse patient populations, aiming to identify evidence‑based best practices, foster implementation, and expand research training opportunities.

Abstract

Developing a national pragmatic clinical trial infrastructure is central to understanding the effectiveness of interventions applied under usual conditions and where people receive health care. To address this challenge, three Florida universities-the University of Florida Clinical and Translational Science Institute, Florida State University (with its community-based distributive medical education model), and the University of Miami-created (2010-2013) a statewide consortium, the OneFlorida Clinical Research Consortium, to support the conduct of pragmatic clinical trials and provide mentored research experiences for medical and graduate students in real-world practice settings.OneFlorida has four programs, which report to a steering committee with membership from each partner, community members, and the state Medicaid agency and Department of Health to ensure shared governance. The Clinical Research Program provides support to conduct research in the network and uses champions to engage community clinicians. The Citizen Scientist Program has community members who provide input on health topics of importance to them, study design, recruitment and retention strategies, and the interpretation of findings. The Data Trust Program contains electronic health record and health care claims data for 10.6 million Floridians. The Minority Education Program, in collaboration with three historically black colleges and universities, offers minority junior faculty mentoring in pragmatic clinical trials and implementation science.OneFlorida has implemented 27 studies with diverse patient populations and in diverse community practice settings.To identify evidence-based best practices from the clinical trials conducted in the network, foster their implementation, and expand research training opportunities.