pH-Responsive Aerobic Nanoparticles for Effective Photodynamic Therapy

Abstract

Due to the unique O₂ self-sufficiency, the nanoparticles, upon irradiation, exhibited higher anticancer activity than free Ce6 both <i>in vitro</i> and <i>in vivo</i>. Our work has identified a new pH-triggered strategy to overcome hypoxia for effective PDT against cancer cells.