Concepedia

Cyclic ureas (DMI, DMPU) as efficient, sustainable ligands in iron-catalyzed C(sp<sup>2</sup>)–C(sp<sup>3</sup>) coupling of aryl chlorides and tosylates

Elwira Bisz, Michal Szostak

Green Chemistry · 2017 · 51 citations · 46 references

DOI

Concepts

Abstract

We report that cyclic ureas (DMI, DMPU) are efficient and sustainable alternatives to reprotoxic NMP in challenging iron-catalyzed C(sp<sup>2</sup>)–C(sp<sup>3</sup>) alkylations of aryl chlorides and tosylates with alkyl Grignard reagents.

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