International Journal of Electrochemical Science · 2017 · 13 citations · 25 references
EngineeringBiomedical EngineeringOncologyBiosensorsElectroanalytical MethodsNanomaterialsCarbon NanotubesElectrochemical BiosensorsElectrochemical DetectionElectrochemical SensorsNanotubesTumor MarkersCancer Biomarker ImmunosensorsCarbon-based ElectrodesCarbon-based Working ElectrodesElectrochemical ImmunosensorsElectrochemical NanobiosensorsElectrochemical NanosensorsNanomaterial-modified Electrodes
This work describes the fabrication of carbon nanotubes (CNTs) incorporated in a carbon paste electrode (CPE) modified by poly-glutamic acid (PGA) for the assessment of CA 153, a breast cancer biomarker. The developed immunosensor was highly sensitive to the level of CA 153 because of the considerably increased charge transfer, and the limit of detection (LOD) was calculated as 0.025 U/mL. The protocol designed for our proposed immunosensor has potential use for clinical study and practical diagnostic applications.
25