Characterization of the phenolic compound, gallic acid from Sansevieria roxburghiana schult and schult. f. rhizomes and antioxidant and cytotoxic activities evaluation

Abstract

<i>Sansevieria roxburghiana</i> has been selected for <i>in vitro</i> antioxidant and cytotoxicity screeningEthyl acetate fraction of methanol extract of <i>S. roxburghiana</i> exhibited effective antioxidant and antiproliferative activitiesThe activity of ethyl acetate fraction may be due to the presence of phenolic compound which is identified by high-performance liquid chromatography and high-performance thin layer chromatography techniques. <b>Abbreviations used:</b> %: Percent, ºC: Celsius, mg: Microgram, ml-Microlitre, ANOVA: Analysis of variance, DMSO: Dimethyl sulfoxide, g: Grams, IC50: Concentration yielding 50% inhibition, Kg: Kilogram, mg: Milligram, min: Minutes, ml: Milliliter, HPLC: High-performance liquid chromatography, HPTLC: High-performance thin layer chromatography, DPPH: 1,1-diphenyl-2-picrylhydrazyl, ABTS: 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt, MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, GAE: Gallic acid equivalents, SRME: Methanol extract of <i>S. roxburghiana</i>, ROS: Reactive oxygen species, SRPE: Petroleum ether fraction of <i>S. roxburghiana</i>, SREA: Ethyl acetate fraction of <i>S. roxburghiana</i>, SRAQ: Aqueous fraction of <i>S. roxburghiana</i>, DMEM: Dulbecco's Minimum Essential Medium, FBS: Fetal bovine serum, OD: Optical density, TPC: Total phenolic content, SRBU: Butanol fraction of <i>S. roxburghiana</i>.