Nanoscale · 2017 · 84 citations · 37 references
PharmacyOncologyPharmacologyChemotherapyDrug DeliveryNanoparticle Drug DeliveryCancer NanomedicineMitochondrial Redox BiologyNanocarriers For TherapeuticsNanomedicineNanoparticle DesignRedox SignalingCancer NanotherapyLipid-polymer Hybrid NanoparticlesMitochondrial Redox SensingMitochondrial Redox SignalingMitochondrial Targeting Of NanoparticlesNanoparticle-based ChemotherapyPolymer-lipid Hybrid NanoparticlesRedox-dependent Activation
under intracellular reductive conditions, resulting in rapid and precise localization in mitochondria. This kind of simple, easy and practicable mitochondria-targeting nanoplatform showed high anticancer activity, and the activatable strategy is valuable for developing a variety of nanocarriers for application in the delivery of other drugs.
37
Self-Assembled Lipid−Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform
Liangfang Zhang, Juliana M. Chan, Frank Gu et al. · ACS Nano · 2008 · 1K citations
ATP-triggered anticancer drug delivery
Ran Mo, Tianyue Jiang, Rocco DiSanto et al. · Nature Communications · 2014 · 676 citations · Full text
Medicine, Oncology, Pharmacology +12
Investigating the optimal size of anticancer nanomedicine
Li Tang, Xujuan Yang, Qian Yin et al. · Proceedings of the National Academy of Sciences · 2014 · 663 citations · Full text
Pharmacy, Oncology, Pharmacokinetics +17