Molecular hybrid design, synthesis and biological evaluation of N-phenyl sulfonamide linked N-acyl hydrazone derivatives functioning as COX-2 inhibitors: new anti-inflammatory, anti-oxidant and anti-bacterial agents

Abstract

The design, synthesis and biological evaluation of the anti-inflammatory activities of novel<italic>N</italic>-phenyl sulfonamide linked<italic>N</italic>-acylhydrazones (NPS–NAH) have been reported.