Concepedia

MicroRNA-486-5p suppresses TGF-β2-induced proliferation, invasion and epithelial–mesenchymal transition of lens epithelial cells by targeting Smad2

Bei Liu, Jianhua Sun, Xiaoqin Lei, Zhongqiao Zhu, Cheng Pei, Qin Li

Journal of Biosciences · 2017 · 33 citations · 19 references

DOI

Concepts

References

19

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

Ronald A. Ignotz, Joan Massagué · Journal of Biological Chemistry · 1986 · 2.5K citations · Full text

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TGF-beta2-induced matrix modification and cell transdifferentiation in the human lens capsular bag.

I. Michael Wormstone, Shigeo Tamiya, Ian Anderson et al. · PubMed · 2002 · 211 citations

, , +11

TGF-β1 induces lens cells to accumulate α-smooth muscle actin, a marker for subcapsular cataracts

Angela M. Hales, Coral G. Chamberlain, John W. McAvoy · Current Eye Research · 1994 · 171 citations

, , +17

Cataract Surgery Induces Retinal Pro-inflammatory Gene Expression and Protein Secretion

Heping Xu, Mei Chen, John V. Forrester et al. · Investigative Ophthalmology & Visual Science · 2010 · 146 citations

, , +17

TGFbeta-Smad signalling in postoperative human lens epithelial cells

Shizuya Saika · British Journal of Ophthalmology · 2002 · 112 citations · Full text

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