Catalyst‐Free Synthesis for Pyrazole‐Fused Isocoumarins in Recyclable and Biodegradable Reaction Medium

Abstract

Abstract An efficient and facile protocol for the synthesis of pyrazole‐fused isocoumarins via reactions of readily available ninhydrin and arylhydrazone is disclosed. This approach illustrate operational simplicity, offering a modified and expedient methodology for the direct construction of synthetically useful pyrazole‐fused isocoumarins compounds in good to excellent yields. This documented strategy, provide a cost effective and environmentally benign alternative to the other existing method.