Microwave‐Assisted Rapid One‐Pot Synthesis of Fused and Non‐Fused Indoles and 5‐[¹⁸F]Fluoroindoles from Phenylazocarboxylates

Abstract

Substituted indoles can be prepared from phenylazocarboxylates through a rapid one-pot sequence featuring a microwave-assisted Fischer indole synthesis as a key step. Considering that the phenylazocarboxylates may beforehand be modified by mild nucleophilic aromatic substitution, including the introduction of [¹⁸ F]fluoride, the overall strategy offers an attractive new access to 5-[¹⁸ F]fluoroindoles.