Prognostic Value of Circulating microRNAs on Heart Failure-Related Morbidity and Mortality in Two Large Diverse Cohorts of General Heart Failure Patients

Abstract

We used a stringent quality assessment for miRNA testing, and were able to replicate the association of miR-1254 and miR-1306-5p with risk of death and HF hospitalization in HF patients of two independent cohorts. However, these two circulating miRNAs failed to improve prognostication over established predictors.