Dosing of Enoxaparin in Renal Impairment.

Abstract

This paper highlights the differences in the pharmacokinetic properties and safety and efficacy outcomes in multiple degrees of renal impairment when using treatment-dose enoxaparin. Given the literature highlighted in this review, a more multitiered enoxaparin renal dosing strategy-perhaps shifting from the current two-tier approach to at least three or four tiers-should be considered.