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Macrolactin F inhibits RANKL-mediated osteoclastogenesis by suppressing Akt, MAPK and NFATc1 pathways and promotes osteoblastogenesis through a BMP-2/smad/Akt/Runx2 signaling pathway

SclerostinBone Morphogenic ProteinCell SignalingMacrolactin FImmunologyOsteoarthritisBmp-2/smad/akt/runx2 Signaling PathwayNfatc1 PathwaysMedicineCell BiologyOsteoporosisCellular PhysiologyOsteocalcinExtracellular Matrix