Concepedia

Neutrophil transfer of <i>miR-223</i> to lung epithelial cells dampens acute lung injury in mice

Viola Neudecker, Kelley S. Brodsky, Eric T. Clambey, Eric P. Schmidt, Thomas Packard, Bennett Davenport, Theodore J. Standiford, Tingting Weng, Ashley A. Fletcher, Lea Barthel,

Science Translational Medicine · 2017 · 175 citations · 47 references

DOI

Concepts

Abstract

Intercellular transfer of miR-223 from neutrophils to alveolar epithelial cells reduces lung inflammation in a mouse model of ventilator-induced lung injury or pulmonary bacterial infection.

References

47

Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice

Yi Chen, Lei Wang, Qiuxiang Kang et al. · Cellular Physiology and Biochemistry · 2017 · 10.7K citations · Full text

, , +17

Neutrophil Extracellular Traps Kill Bacteria

Volker Brinkmann, Ulrike Reichard, Christian Goosmann et al. · Science · 2004 · 10.1K citations

, , +17

Acute Respiratory Distress Syndrome

Ards Definition Task Force · JAMA · 2012 · 8.8K citations

, , +8

Most mammalian mRNAs are conserved targets of microRNAs

Robin C. Friedman, Kyle Kai‐How Farh, Christopher B. Burge et al. · Genome Research · 2008 · 8.6K citations · Full text

, , +15

Neutrophil emigration in the skin, lungs, and peritoneum: different requirements for CD11/CD18 revealed by CD18-deficient mice.

PubMed · 1997 · 7.1K citations · Full text

, , +15