Comparative evaluation of 18F-FLT and 18F-FDG for detecting cardiac and extra-cardiac thoracic involvement in patients with newly diagnosed sarcoidosis

Abstract

The results of this preliminary study suggest that ¹⁸F-FLT PET/CT can detect cardiac and extra-cardiac thoracic involvement in patients with newly diagnosed sarcoidosis as well as ¹⁸F-FDG PET/CT, although uptake of ¹⁸F-FLT in lesions was significantly lower than that of ¹⁸F-FDG. However, ¹⁸F-FLT PET/CT may be easier to perform since it requires neither prolonged fasting nor a special diet prior to imaging.