Concepedia

Publication | Open Access

A multifunctional nanocarrier for efficient TRAIL‐based gene therapy against hepatocellular carcinoma with desmoplasia in mice

DOIFull Paper Access

51

Citations

26

References

2017

Year

Chun‐Hung Liu, Guann‐Jen Chern, Fu‐Fei Hsu, Kuan‐Wei Huang, Yun‐Chieh Sung, Hsi‐Chien Huang, Jian‐Tai Qiu, Sheng‐Kai Wang, Chu‐Chi Lin, Chien‐Hsun Wu,
Hepatology

Abstract

TRAIL pDNA delivered by HCC-targeted LCPP NPs in combination with conventional sorafenib treatment attenuated HCC progression as well as liver fibrosis. Overall, our study presents an effective TRAIL-based cancer therapy that could be developed for clinical applications. (Hepatology 2018;67:899-913).

References

YearCitations

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