Progress in C—N Bonds Formation Using t-BuONO

Abstract

The formation of C-N bonds by nitration is a powerful strategy for organic synthesis. Recently, the remarkable progress has been made in synthesis of nitrogen compounds using tert-butyl nitrite as nitration reagent. The present protocol, with a mild reaction condition and an excellent region selectivity, provides a green and efficient approach to construct C-N bonds. This review will summarize the recent development in this area on the basis of different substrates systems.