Role of TLRs and IL-6 in the outcome of chronic hepatitis C treatment in Tunisian population

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Lena Alexopoulou, Agnieszka Czopik Holt, Ruslan Medzhitov et al. · Nature · 2001 · 6.1K citations

Life Sciences, Immunology, Molecular Biology +14

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis.

Daniel Fishman, Gary Faulds, Rachel Jeffery et al. · Journal of Clinical Investigation · 1998 · 2.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

Yasuhito Tanaka, Nao Nishida, Masaya Sugiyama et al. · Nature Genetics · 2009 · 2.1K citations

Life Sciences, Immunology, Pharmacology +16

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

Nancy C. Arbour, Eva Lorenz, Brian C. Schutte et al. · Nature Genetics · 2000 · 2K citations

Life Sciences, Genetics, Immunology +10

IL-28, IL-29 and their class II cytokine receptor IL-28R

Paul O. Sheppard, Wayne Kindsvogel, Wenfeng Xu et al. · Nature Immunology · 2002 · 1.6K citations

Life Sciences, Immunology, Clinical Immunology +7