Blood · 2017 · 396 citations · 32 references
MedicineHematologyOncologyCancer GeneticsHematologic OncologyMolecular OncologyCancer ImmunotherapyHematologic MalignanciesHematologic Malignancy TherapyLymphoid NeoplasmsLymphoid TumorsMalignant NeoplasmsP53 AbnormalityP53 MutationP53 Pathway AlterationsP53 Pathway InactivationTp53 Mutations
Key Points The intensified standard-of-care regimens for younger patients with MCL do not overcome the deleterious effects of TP53 mutations. MCLs with TP53 mutations should be considered for alternative frontline treatment.
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