Homology Modeling and Molecular Docking Studies of Bacillomycin and Iturin Synthetases with Novel Ligands for the Production of Therapeutic Lipopeptides

Abstract

The knowledge of the docking sites and docking characteristics of the lipopeptide synthetases mentioned in the paper with the ligands can provide advantages of high speed and reliability, reduced costs on chemicals and experiments and the ethical issues concerned with the use of animal models for screening of drug toxicity.