Rome <scp>III</scp> vs Rome <scp>IV</scp> criteria for irritable bowel syndrome: A comparison of clinical characteristics in a large cohort study

Abstract

The Rome IV IBS population likely reflects a subgroup of Rome III IBS patients with more severe GI symptomatology, psychological comorbidities, and lower quality of life. This implies that results from Rome III IBS studies may not be directly comparable to those from Rome IV IBS populations.