Publication | Closed Access
Tf2NH-Catalyzed 1,6-Conjugate Addition of Vinyl Azides with p-Quinone Methides: A Mild and Efficient Method for the Synthesis of β-Bis-Arylamides
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Citations
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References
2017
Year
Combinatorial ChemistryP-quinone MethidesChemical EngineeringBroad Substrate ScopeEngineeringCross-coupling ReactionNatural SciencesDiversity-oriented SynthesisTf2nh-catalyzed 1,6-Conjugate AdditionVinyl AzidesOrganic ChemistryCatalysisChemistrySynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering
Tf2NH-catalyzed tandem 1,6-conjugate addition/Schmidt type rearrangement using vinyl azides and p-quinone methides to access a variety of β-bis-arylated amides is reported. The method is quick, efficient, mild, and high yielding with broad substrate scope.
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