WHO Needs High FIO2?

Abstract

<i>World Health Organization</i> and the <i>United States Center for Disease Control</i> have recently recommended the use of 0.8 FIO₂ in all adult surgical patients undergoing general anaesthesia, to prevent surgical site infections. This recommendation has arisen several discussions: As a matter of fact, there are numerous studies with different results about the effect of FIO₂ on surgical site infection. Moreover, the clinical effects of FIO₂ are not limited to infection control. We asked some prominent authors about their comments regarding the recent recommendations.