Colletotrichine A, a new sesquiterpenoid from <i>Colletotrichum gloeosporioides</i> GT-7, a fungal endophyte of <i>Uncaria rhynchophylla</i>

Abstract

One new compound, Colletotrichine A (1), was produced by the fungal Colletotrichum gloeosporioides GT-7. The structure was established by 1D and 2D NMR spectra. Monoamine oxidase (MAO) and acetylcholinesterase (AChE) inhibitory activity of 1 was also evaluated. Compound 1 showed AChE-inhibiting activity with IC₅₀ value of 28 μg/mL.