Iron overload down-regulates the expression of the HIV-1 Rev cofactor eIF5A in infected T lymphocytes - Concepedia

Concepedia

Publication | Open Access

Iron overload down-regulates the expression of the HIV-1 Rev cofactor eIF5A in infected T lymphocytes

DOI Full Paper Access

14

Citations

27

References

2017

Year

Carmine Mancone, Alessio Grimaldi, Giulia Refolo, Isabella Abbate, Gabriella Rozera, Dario Benelli, Gian María Fimia, Vincenzo Barnaba, Marco Tripodi, Mauro Piacentini,

Proteome Science

Abstract

Our study indicates that HIV-1 cofactors influenced by iron metabolism represent potential targets for antiretroviral therapy and suggests eIF5A as a selective target for drug development.

References

	Year	Citations

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