Anticancer Effects of Baicalein in Pancreatic Neuroendocrine Tumors In Vitro and In Vivo

Abstract

Baicalein could increase caspase-3 and Bax expression and decrease survivin and Bcl-2 to induce apoptosis. It inhibits migration and invasion by decreasing expression of vascular endothelial growth factor and matrix metalloproteinases 2 and 9.